UKRMP Regenerative Medicine 2023 – Save the Dates 8-10 Nov, Edinburgh

By | Acellular / smart materials – 3D architecture, Engineered cell environment, Latest, News, Pluripotent stem cells and engineered cells, Uncategorized

Meeting Focus:
Addressing the Key Translational Challenges of Regenerative Medicine.

Meeting Aim:
To showcase 10 years of UK regenerative medicine translational research and build on the success of UKRMP translational outputs, industrial collaborations and clinical application.

Who Should Attend?
Anyone with an interest in Regenerative Medicine, tools and techniques for cutting edge science and progress from bench to bedside.

Confirmed Speakers:

  • Rawiya Al Hosni, Postdoctoral Researcher, University of Cambridge, UK
  • Ivana Barbaric, Professor, University of Sheffield, UK
  • Roger Barker, Professor, University of Cambridge, UK
  • Jacqueline Barry, Chief Clinical Officer, Cell and Gene Therapy Catapult, UK
  • Catherine Beltran-Rendon, Postdoctoral Researcher, Loughborough University, UK
  • Robin Buckle, Chief Science Officer, Medical Research Council, UK
  • Neil Carragher, Professor, University of Edinburgh, UK
  • Jonathan Dawson, Associate Professor, University of Southampton, UK
  • Charlotte Durkin, Head of Multimodal and Multiscale Biology, Medical Research Council, UK
  • Alicia El Haj, Professor, University of Birmingham, UK
  • Elaine Emmerson, RCUK/UKRI Innovation Fellow & Chancellor’s Fellow, University of Edinburgh, UK
  • Stuart Forbes, Professor, University of Edinburgh, UK
  • Victoria Gadd, Postdoctoral Research Fellow, University of Edinburgh, UK
  • Cedric Ghevaert, Professor, University of Cambridge, UK
  • David Hay, Professor, University of Edinburgh, UK/Founder, Chairman and CEO, Stimuliver, Denmark
  • Zoe Hewitt, Co-Founder and CEO, Regenerative Cell Therapy Consulting Ltd, UK
  • Yuki Ishii, Postdoctoral Researcher, University College London, UK
  • Agnieszka Janeczek, Founder and CEO, Renovos, UK
  • Joanne Jones, Associate Professor, University of Cambridge, UK
  • Janos Kanczler, Lecturer, University of Southampton, UK
  • Owen Laing, PhD Student, University of Sheffield, UK
  • Hannah Levis, Senior Lecturer, University of Liverpool, UK
  • Andrew McCaskie, Professor, University of Cambridge, UK
  • Florian Merkle, Principle Investigator, University of Cambridge, UK
  • Pierre-Alexis Mouthuy, Associate Professor, University of Oxford, UK
  • Marko Nikolic, MRC Clinician Scientist Fellow, University College London, UK
  • Malin Palmer, Professor, Lund University, Sweden
  • Rachael Pearson, Professor, King’s College London, UK
  • Graziella Pellegrini, Professor, University of Modena and Reggio Emilia, Italy
  • Jelle Penders, Co-founder and CEO, SPARTA Biodiscovery Ltd, UK
  • Felicity Rose, Professor, University of Nottingham, UK
  • Kourosh Saeb-Parsy, Professor, University of Cambridge, UK
  • Manuel Salmeron-Sanchez, Professor, University of Glasgow, UK
  • Stefan Schoenfelder, Career Progression Fellow, Babraham Institute, UK
  • Hazel Screen, Professor, Queen Mary University of London, UK
  • Molly Stevens, Professor, University of Oxford and Imperial College London, UK
  • Sarah Waters, Professor, University of Oxford, UK
  • Lisa White, Associate Professor, University of Nottingham, UK
  • Jonathan Wojciechowski, Postdoctoral Research Associate, Imperial College London, UK

Location:
Hosted by the University of Edinburgh at the McEwan Hall, Teviot Place, Edinburgh, EH8 9AG.
On Wed 8 Nov 2023 to Fri 10 Nov 2023.

Networking Opportunities:
Exhibitors Hall – Opening at Registration Wed 8 Nov (Noon) to close on Fri 10 Nov (Noon).
Networking evening at McEwan Hall with hot buffet – Wed 8 Nov.
Gala Dinner at Dynamic Earth – 3 course dinner – Thu 9 Nov.

Registration: 
Details of how to register, deadlines and prices to be confirmed.

Sponsorship Opportunities:
We have a number of Sponsorship opportunities available, if you are interesting in being a sponsor or which to exhibit, please contact Julie Wallace for information.

UKRMP to exhibit at the 2021 Till & McCulloch Meeting hosted by the Stem Cell Network, Canada

By | Acellular / smart materials – 3D architecture, Engineered cell environment, Latest, News, Pluripotent stem cells and engineered cells

In our continued efforts to develop strong international partnerships, the UKRMP Hubs will be exhibiting (virtually) at The 2021 Till & McCulloch Meeting (TMM) – hosted by the Canadian Stem Cell Network from November 15 to 17.

Celebrating is 10th year, the Till & McCulloch Meetings are named after Canadian researchers Drs. James Till & Ernest McCulloch, who definitively proved the existence of stem cells in 1961. The TMM is Canada’s largest stem cell research and regenerative medicine conference.  This is a great opportunity to discover what Canada’s leading stem cell scientists, clinicians, bioengineers and ethicists, as well as representatives from industry, government, health and NGO sectors have to offer.

To find out more visit: https://stemcellnetwork.ca or click here.

High Throughput Screening Workshop – Hosted by the ECE Hub.

By | Engineered cell environment, Event, Latest, News

High Throughput Screening Workshop – the latest in complex cell-based assay screening
Tuesday 22 March 2022, The Frances Crick Institute, London
Hosted by the UKRMP Engineered Cell Environment Hub.

Find out about the latest cutting edge in cell based assays technologies and learn directly from high profile industry and academic experts about their innovative research in the development of complex biological models in High Throughput Screening. This workshop brings together experts from distinct fields of complex cell model development, and cell based phenotypic screening, high content image analysis and downstream informatics solutions.

Keynote: Prof Chris Bakal, Dynamic Cell Systems Lab, Imperial College.

Confirmed speakers: Davide Gianni, Senior Director of Functional Genomics, AstraZeneca and Henriette Lanz, Director Model Development, Mimetas.

This Workshop is free to attend, however you must register online once registration opens, details to follow.

For more information please contact Robin Morton 

New Paper: Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition

By | News, Pluripotent stem cells and engineered cells
Chris Price (PDRA)
Dylan Stavish (PDRA)

As human pluripotent stem cell (hPSC) derived-cell therapies progress into the clinic, one of the challenges we are addressing surrounds the safety of hPSC derivates for use in cellular therapies. A key aspect of this work entails assessing how cells that acquire common chromosomal abnormalities can overtake the existing normal wild-type population.

Researchers (Christopher Price, PhD and Dylan Stavish) from the  Pluripotent Stem Cell and Engineered Cell (PSEC) Hub based at The University of Sheffield, led by Dr Ivana Barbaric, describe in a recent Developmental Cell article, a selection mechanism that facilitates genetically variant cells achieving clonal dominance by eliminating wild-type through YAP mediated cell competition.

https://lnkd.in/dYNDdy8b

By understanding the attributes and culture conditions that encourage genetically variant cells, this work provides a platform for future development and optimization of hPSC culture conditions to safely expand cells for regenerative medicine.

 

Ivana Barbaric (PI Sheffield)

New Paper: Process analysis of pluripotent stem cell differentiation to megakaryocytes to make platelets applying European GMP

By | News, Pluripotent stem cells and engineered cells
Moyra Lawrence (PDRA)

In their new npj Regenerative Medicine paper, PSEC researcher Dr Moyra Lawrence, from the University of Cambridge, in partnership with other researchers from the Cambridge Stem Cell Institute and the Cell and Gene Therapy Catapult, describe the process analysis of megakaryocyte manufacture from iPSCs with a view to manufacturing in vitro platelets to European GMP for transfusion. These general principles will help other cell therapy developers on their translational journey.

Cedric Ghevaert (Deputy Director and PI Cambridge & Deputy Director)